Research chemical,medical intermediate,Pharmaceutical chemicals
Methylone, also known as "M1", 3,4-methylenedioxy-N-methylcathinone, bk-MDMA, is an entactogen and stimulant of the phenethylamine, amphetamine, and cathinone classes. It was originally patented by Jacob Peyton and Alexander Shulgin in 1996 as an antidepressant. The more intuitive abbreviation MDMC unfortunately can not be used for this chemical, since it had already been given to another earlier Shulgin creation, 3,4-ethylenedioxymethamphetamine. Methylone is a close structural analogue of MDMA, differing by the addition of a β-ketone group. Reported dosages range from 100 to 250 mg orally. Some respondents say that increasing dose with methylone beyond 100–180 mg causes increased physical effects and does not substantially improve the empathic cognitive effects.
Methylone resembles MDMA in its behavioural profile, as it substitutes for MDMA in rats trained to discriminate MDMA from saline. Methylone does not substitute for amphetamine or for the hallucinogenic DOM in animals trained to discriminate between these drugs and saline. Further, also in common with MDMA, methylone acts on monoaminergic systems. In vitro, methylone has one third the potency of MDMA at inhibiting platelet serotonin accumulation and about the same in its inhibiting effects on the dopamine and noradrenaline transporters.
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dissociative anesthetic:3-MeO-PCP 4-MeO-PCP Diphenidine 2-Oxo-PCM(Deschloroketamine)
5F-NPB22 4-MEO-PVP BB-22 5-MMA 4-MeMABP ADSB-FUB-187 2-FDCK
Isopropylphenidate N-Ethyl-Hexedrone Hexen
Alprazolam Etizolam diazepam clonazepam oxycodone hydrocodone zolpidem phentermine
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